Properties of the Causative Agent of a Chicken Tumor
نویسنده
چکیده
The fractionation of active chicken tumor extracts has been continued. 1. By a rapid method of dialysis the diffusible fraction of the treated extract, representing about 75 per cent of the solids, has been eliminated without reducing the tumor-producing activity. 2. Combined methods of fractionation have resulted in the elimination of as much as 95 per cent of the total solids of the extract as inactive constituents. Since there was some concomitant enhancement of the activity of the agent the results were equivalent to a 25-fold concentration of it in terms of dry weight. 3. The chemical content of the undiffusible fraction has been determined in terms of total nitrogen, reducing substances, sulfur, phosphorus, and lipoids. 4. The evidence points to a protein and a phospholipoid as the principal constituents of the active residue. Further fractionation is being attempted with a view to connecting the tumor-producing activity with one of its remaining constituents.
منابع مشابه
Properties of the Causative Agent of a Chicken Tumor X. Chemical Properties of Chicken Tumor Extracts by Albert Claude, M.d
متن کامل
Biological properties, therapeutic and diagnostic applications of Samarium and Samarium nanoparticles
Lanthanides are a family of elements, commonly known as rare earth elements. Metal samarium as one of the most important member of this family, which plays very important roles in the diagnosis and treatment of various diseases, especially cancer. Several lanthanide complexes, samarium in particular, have shown anticancer effects on tumor cells. This paper is tried to review the biological prop...
متن کاملProperties of the Causative Agent of a Chicken Tumor Iii. Attempts at Isolation of the Active Principle* By
Since the demonstration of the transmissibility of chicken tumors by agents separable from the malignant cells, the relationship of this group of neoplasms to those of the mammalian type has been a question of first importance. At first it was generally considered that the chicken tumor agents belonged to the virus group of organisms. This conclusion led to some doubt that the chicken tumors re...
متن کاملA Study on the Rate of Contamination of Slaughtered Chicken by Campylobacter in Industrial Slaughter Houses
SUMMARY Campylobacters are gram negative, microaerophilic, curved or spiral shaped organisms, among which C.jejuni is considered as the most common causative agent of bacterial gastroenteritis in human. It is likely to be transmitted by consumption of animal products as well as poultry. So a potential source of infection could be traced to the chicken abattoirs in order to determine the rate o...
متن کاملDigestive alkaline proteases from the Tunisian barbell (Barbus callensis): Characterization and application as a detergent additive, in chicken feather-degradation and as a dehairing agent
Alkaline crude enzymes from the viscera of the Tunisian barbel (Barbus callensis) were extracted and characterized. Proteolytic crude extract from barbel viscera was active and stable in alkaline solution. The optimum pH and temperature were 11.0 and 55 °C, respectively, using casein as a substrate. The crude alkaline protease was extremely stable in the pH range of 5.0-12.0. Zymography activit...
متن کاملMonitoring the prevalence of the tetracycline efflux genes among E. coli isolated from chicken colibacillosis
BACKGROUND: Avian Colibacillosis can lead to important economic losses in the poultry industry. Escherichia coli the causative agent of this disease has acquired resistance to different antibiotics, including tetracycline. OBJECTIVES: This study was carried out to detect the distribution of tetracycline Group І efflux genes genes among E.coli isolates from from avian colibacillosis in Iran by P...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 56 شماره
صفحات -
تاریخ انتشار 1937